Publications

  1. Barragán GA, Cerda DA de la, Landoni E, Dholakia K, Humeniuk P, … Rios X, Caraballo LD, et al. IL-18 metabolically reprograms CAR-expressing natural killer T cells and enhances their antitumor activity against neuroblastoma [Internet]. bioRxiv; 2025 [cited 2025 May 23]. p. 2025.04.18.649551.

  2. Tian G, Barragan G, Yu H, Adaikkalavan A, Rios X, Amador C, Guo L, Drabek J, Pardias O, Montalbano A, Zhang C, Li Y, Courtney A, Metelitsa L 1. Tian G, PRDM1 Is a Key Regulator of the NKT-cell Central Memory Program and Effector Function. Cancer Immunology Research. 2025 Apr 2;13(4):577–90.

  3. Rios X, Pardias O, Morales MA, Bhattacharya P, Chen Y, Guo L, et al. Refining chimeric antigen receptors via barcoded protein domain combination pooled screening. Molecular Therapy. 2023 Nov 1;31(11):3210–24.

  4. McEvoy MT, Stuckert AJ, Castellanos MI, Gilbert MM, Pfeiffer T, Prudowsky Z, Rios X, et al. Management of nutritional iron deficiency anemia for young children in the emergency department. Pediatric Blood & Cancer. 2023;70(3):e30181.

  5. Filsinger GT, Wannier TM, Pedersen FB, Lutz ID, Zhang J, Stork DA, Debnath A, Gozzi K, Kuchwara H, Volf V, Wang S, Rios X, Gregg CJ, Lajoie MJ, Shipman SL, Aach J, Laub MT, Church GM. Characterizing the portability of phage-encoded homologous recombination proteins. Nat Chem Biol. 2021 Apr;17(4):394-402. doi: 10.1038/s41589-020-00710-5. Epub 2021 Jan 18. PMID: 33462496; PMCID: PMC7990699.

  6. Wannier, T. M., Nyerges, A., Kuchwara, H. M., Czikkely, M., Balogh, D., Filsinger, G. T., Borders, N. C., Gregg, C. J., Lajoie, M. J., Rios, X., Pál, C., & Church, G. M. (2020). Improved bacterial recombineering by parallelized protein discovery. Proc Natl Acad Sci U S A. 2020;202001588. doi:10.1073/pnas.2001588117

  7. Rios X, Chinn IK, Orange JS, Hanson CI, Rider NL. T-Cell Lymphopenia Detected by Newborn Screening in Two Siblings with an Xq13.1 Duplication. Front Pediatr. 2017 Jul 18;5:156. doi: 10.3389/fped.2017.00156. eCollection 2017.

  8. Wang, G.*, Yang, L.*, Grishin, D.*, Rios, X.*, Ye, L. Y., Hu, Y., Li, K., Zhang, D., Church, G. M., & Pu, W. T. (2017). Efficient, footprint-free human iPSC genome editing by consolidation of Cas9/CRISPR and piggyBac technologies. Nature protocols, 12(1), 88–103. https://doi.org/10.1038/nprot.2016.152
    * contributed equally to this study

  9. Feng J, Jester BW, Tinberg CE, Mandell DJ, Antunes MS, Chari R, Morey KJ, Rios X, Medford JI, Church GM, Fields S, Baker D. A general strategy to construct small molecule biosensors in eukaryotes. Elife. 2015 Dec 29;4. PMID: 26714111

  10. Lee JH, Daugharthy ER, Scheiman J, Kalhor R, Yang JL, Ferrante TC, Terry R, Jeanty SS, Li C, Amamoto R, Peters DT, Turczyk BM, Marblestone AH, Inverso SA,Bernard A, Mali P, Rios X, Aach J, Church GM. Highly multiplexed subcellular RNA sequencing in situ. Science. 2014 Mar 21;343(6177):1360-3.

  11.  Yang L, Guell M, Byrne S, Yang JL, De Los Angeles A, Mali P, Aach J, Kim-Kiselak C, Briggs AW, Rios X, Huang PY, Daley G, Church G. Optimization of scarless human stem cell genome editing. Nucleic Acids Res. 2013 Oct;41(19):9049-61.

  12. DiCarlo JE, Norville JE, Mali P, Rios X, Aach J, Church GM. Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems. Nucleic Acids Res. 2013 Apr;41(7):4336-43.

  13. Briggs AW, Rios X, Chari R, Yang L, Zhang F, Mali P, Church GM. Iterative capped assembly: rapid and scalable synthesis of repeat-module DNA such as TAL effectors from individual monomers. Nucleic Acids Res. 2012 Aug;40(15):e117

  14. Rios X, Briggs AW, Christodoulou D, Gorham JM, Seidman JG, Church GM. Stable gene targeting in human cells using single-strand oligonucleotides with modified bases. PLoS One. 2012;7(5):e36697.

  15. Hurle B, Ignatova E, Massironi SM, Mashimo T, Rios X, Thalmann I, Thalmann R, Ornitz DM. Non-syndromic vestibular disorder with otoconial agenesis in